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Aeruginosin 865
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Aeruginosin 865图片
CAS NO:1611990-01-2
包装:5 mg
市场价:7000元

产品介绍

产品描述

Aeruginosin 865, isolated from terrestrial cyanobacterium Nostoc sp . Luke ová 30/93, is the first aeruginosin-type peptide containing both a fatty acid and a carbohydrate moiety. Aeruginosin 865 inhibits translocation of NF-kB to the nucleus. Aeruginosin 865 has anti-inflammatory effect

体外活性

Aeruginosin 865 (pretreatment with 0.1-100 μg/mL) shows significant inhibition of IL-8 (EC 50 =3.5 μg/mL) and ICAM-1 (EC 50 =50.0 μg/mL) in hTNF-α-stimulated HLMVECs in a concentration-dependent manner. Aeruginosin 865 does not affect cell viability, even at much higher concentration in HeLa, HepG2 cells[1]. Aeruginosin 865 (100-200 μM) shows high-dose cytotoxicity in Mouse fibrosarcoma cells and with no cytotoxic effect in NIH/3T3 cells[2]. .

Cas No.

1611990-01-2

分子式

C41H64N6O14

分子量

864.991

别名

Aeruginosin 865

储存和溶解度

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years