Imlunestrant (LY3484356) 是具有口服活性的选择性雌激素受体的降解剂(SERD)。Imlunestrant (LY3484356) 可用以ER+ 和HER2 乳腺癌。

Imlunestrant (LY3484356) is an orally active selective estrogen receptor (ER) degrader (SERD). Imlunestrant (LY3484356) could be used in the study for ER+, HER2-advanced breast cancer [1].

Imlunestrant (LY3484356) shows favorable efficacy and pharmacokinetic (PK) properties, including antitumor activity in ESR1 mutants [1]. Imlunestrant (LY3484356) is a potent degrader and selective pure antagonist of wild type and mutant ERα [2].

2408840-26-4

C29H24F4N2O3

524.51

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years