DCN1-UBC12-IN-2 是一种有效且特异性的DCN1-UBC12抑制剂(IC50= 9.55 nM)。DCN1-UBC12-IN-2 可特异性靶向 DCN1-UBC12 相互作用并缓解 Ang II 诱导的心脏成纤维细胞活化。

DCN1-UBC12-IN-2 is a potent and specific DCN1-UBC12 inhibitor ( IC 50 =9.55 nM). DCN1-UBC12-IN-2 could specifically target DCN1-UBC12 interaction and relieve Ang II-induced cardiac fibroblast activation [1].

DCN1-UBC12-IN-2 (DN-2) possesses relatively low cytotoxicity toward cardiac fibroblasts (CFs) with an IC 50 of 27.34 μM for 24 h.

2374827-47-9

C23H20ClN7O3S2

542.03

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years