NEUROTENSIN TFA (39379-15-2 free base) 是一种内源性 13 个氨基酸的神经肽,具有显着的阿片类非依赖性镇痛作用。它在大脑中充当神经递质,在肠道中充当激素,也充当神经调节剂。由于它与多种神经递质系统如多巴胺能、血清素能、谷氨酸能、GABA能和胆碱能系统。它具有作为人体代谢物、有丝分裂原、神经递质和创伤的作用。
产品描述
Neurotensin (NT) is an endogenous 13 amino acid neuropeptide with profound opioid-independent analgesic effects. It behaves as a neurotransmitter in the brain, as a hormone in the gut, and also as a neuromodulator. It is implicated in the pathophysiology of several CNS disorders (including schizophrenia, Parkinson's disease, drug abuse, pain, cancer, inflammation, eating disorders and central control of blood pressure) due to its association with a wide variety of neurotransmitter systems such as dopaminergic, sertonergic, glutamatergic, GABAergic, and cholinergic systems. It has a role as a human metabolite, a mitogen, a neurotransmitter and a vulnerary.
Cas No.
TP2309
分子式
C78H121N21O20
分子量
1672.92
别名
NEUROTENSIN TFA;神经加压素;Pyr-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Tyr-Ile-Leu-OH TFA(55508-42-4 free base);NEUROTENSIN TFA (39379-15-2 free base)
储存和溶解度
DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years