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Diprotin A TFA
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Diprotin A TFA图片
CAS NO:209248-71-5
包装:500 mg
市场价:15425元

产品名称
Ile-Pro-Pro (TFA)
产品介绍

产品描述

Diprotin A (TFA) is an inhibitor of dipeptidyl peptidase IV (DPP-IV).

体外活性

Diprotin A can increase the phosphorylation of Src and vascular endothelial cadherin (VE-cadherin) in human endothelial cells and destroy the connection between endothelial cells, which can be blocked by CXCR4 (SDF-1α receptor) or Src inhibitor Weaken.

体内活性

Diprotin A collectively induces vascular leakage by increasing the SDF-1α/CXCR4/Src/VE-cadherin signaling pathway. In the model of retinopathy of prematurity, Diprotin A will not only increase retinal blood vessels, but also increase leakage. In addition, in the murine model of diabetic retinopathy, bupstatin A increases the phosphorylation of Src and VE-cadherin and aggravates retinal vascular leakage.

Cas No.

209248-71-5

分子式

C19H32F3N3O6

分子量

455.47

别名

Ile-Pro-Pro (TFA);Diprotin A TFA

储存和溶解度

H2O:77.5 mg/mL (170.15 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years