Axl-IN-8 (NO.1) 是一种有效的AXL抑制剂,其IC50低于 1 nM。Axl-IN-8 也抑制c-MET,IC50在 1-10 nM 之间。Axl-IN-8 对 BaF3/TEL-AXL、MKN45 和 EBC-1 细胞均有抗增殖活性,其IC50值分别为<10、226.6 和 120.3 nM。
产品描述
Axl-IN-8 (NO.1) is a potent AXL inhibitor, with an IC 50 of<1 nM. Axl-IN-8 also inhibits c-MET, with an IC 50 of 1-10 nM. Axl-IN-8 shows anti-proliferative activity against BaF3/TEL-AXL, MKN45, and EBC-1 cells, with IC 50 values of<10, 226.6 and 120.3 nM, respectively [1].
Cas No.
2231424-62-5
分子式
C31H29FN6O3
分子量
552.6
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years