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DNA-PK-IN-5
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAS NO:2719736-43-1
包装与价格:
包装价格(元)
5 mg电议
50 mg电议
100 mg电议

产品介绍
DNA-PK-IN-5 是一种有效的DNA-PK抑制剂。DNA-PK-IN-5 抑制 DNA-PKCs 活性,从而大大降低肿瘤 DNA 修复并诱导细胞进入凋亡程序。DNA-PK-IN-5 增强肿瘤组织对放疗的敏感性,克服耐药问题,增强对多种实体瘤和血液肿瘤的抑制作用 (摘自专利 WO2021204111A1,化合物 2)[ 1]。

产品描述

DNA-PK-IN-5 is a potent inhibitor of DNA-PK. DNA-PK-IN-5 inhibits DNA-PKcs activity, thus greatly reducing tumor DNA repair and inducing cells to enter the apoptotic program. DNA-PK-IN-5 enhances the sensitivity of tumor tissues to radiotherapy, overcomes the problem of drug resistance, and enhances the inhibitory effect on a variety of solid tumors and hematological tumors (extracted from patent WO2021204111A1, compound 2) [1].

Cas No.

2719736-43-1

分子式

C21H22N8O2

分子量

418.45

储存和溶解度

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years