产品描述
Pomalidomide-PEG3-C2-NH2 (Cereblon Ligand-Linker Conjugates 5) hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology.
体外活性
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2].
Cas No.
2446474-09-3
分子式
C21H29ClN4O7
分子量
484.93
别名
E3ligaseLigand-LinkerConjugates30hydrochloride;Cereblon Ligand-Linker Conjugates 5 hydrochloride;Pomalidomide-PEG3-C2-NH2 hydrochloride;Pomalidomide-PEG3-C2-NH2 hydrochloride
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years