您好,欢迎来到化工原料网! [登录] [免费注册]
化工原料网
位置:首页 > 产品库 > (S,R,S)-AHPC-PEG3-N3
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
(S,R,S)-AHPC-PEG3-N3
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
(S,R,S)-AHPC-PEG3-N3图片
CAS NO:1797406-80-4
包装与价格:
包装价格(元)
2 mg电议
5 mg电议
10 mg电议
25 mg电议
50 mg电议
100 mg电议
200 mg电议
500 mg电议

产品名称
E3 ligase Ligand-Linker Conjugates 12
VHL Ligand-Linker Conjugates 8
VH032-PEG3-N3
产品介绍
(S,R,S)-AHPC-PEG3-N3 包含基于 (S,R,S)-AHPC 的 VHL 配体和 3 个单元 PEG linker,是一种合成的 E3 连接酶配体-linker 偶联物。

产品描述

(S,R,S)-AHPC-PEG3-N3 is a synthesized E3 ligase ligand-linker conjugate. (S,R,S)-AHPC-PEG3-N3 incorporates the (S,R,S)-AHPC based VHL ligand and 3-unit PEG linker used in PROTAC technology.

体外活性

(S,R,S)-AHPC-PEG3-N3 is extracted from patent WO/2016/146985A1, figure 11. PROTAC has been developed with an A-L-B structure that can tether a bromodomain inhibitor via a moiety which binds to a protein within the bromo- and Extra-terminal (BET) family of proteins to a small molecule E3 ubiquintin ligase protein binding ligand compound via a suitable linker[1][2].

Cas No.

1797406-80-4

分子式

C30H43N7O7S

分子量

645.77

别名

E3 ligase Ligand-Linker Conjugates 12;VHL Ligand-Linker Conjugates 8;VH032-PEG3-N3;(S,R,S)-AHPC-PEG3-N3

储存和溶解度

DMSO:50 mg/mL (77.43 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years