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BMS-654457
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
BMS-654457图片
CAS NO:1004551-41-0
包装:5 mg
市场价:9850元

产品介绍

产品描述

BMS-654457 is a small-molecule, reversible inhibitor of factor XIa (FXIa; Kis: 0.2 and 0.42 nM for human and rabbit FXIa).

体外活性

BMS-654457 shows comparable in vitro potency against FXIa and was over 500-fold selective against coagulation-related proteases (thrombin, FXa, and FVIIa) in these species.

体内活性

BMS-654457 is potent in the prevention of arterial thrombosis in rabbits with limited effects on bleeding time.

Cas No.

1004551-41-0

分子式

C36H37N5O4

分子量

603.71

别名

BMS-654457

储存和溶解度

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years