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TCMDC-135051 TFA(2413716-15-9 free base)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
TCMDC-135051 TFA(2413716-15-9 free base)图片
包装与价格:
包装价格(元)
100 mg电议
500 mg电议

产品名称
TCMDC-135051 TFA
TCMDC-135051 TFA (2413716-15-9 free base)
产品介绍

产品描述

TCMDC-135051 TFA is a highly selective and potent inhibitor of protein kinase PfCLK3.

体外活性

In a liver invasion and development assay, TCMDC-135051 TFA shows potent activity against P. berghei sporozoites in which the compound shows a pEC50 value of 6.17 (EC50=0.40 μM) . The kinase assays using recombinant PvCLK3 (P. vivax) and PbCLK3 (P. berghei) show that TCMDC-135051 TFA has near-equipotent inhibition at these two orthologs, with pIC50 values of 7.47 (IC50=0.033 μM) and 7.86 (IC50=0.013 μM), respectively.

Cas No.

T13102L

分子式

C31H34F3N3O5

分子量

585.61

别名

TCMDC-135051 TFA;TCMDC-135051 TFA (2413716-15-9 free base)

储存和溶解度

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years