Phenylbiguanide 是一种 5-HT3 受体选择性激动剂，EC50为 3.0±0.1 μM。

Phenylbiguanide is a 5-HT3 receptor selective agonist(EC50 : 3.0±0.1 μM)

Phenylbiguanide (PBG) is a drug known to stimulate cardiopulmonary afferent C-fibres. PBG is injected into the right atrium of the heart in anaesthetised mice and mapped c-Fos expression within specific regions of the central nervous system. Intraatrial injection of PBG produces a reflex cardiorespiratory response including a pronounced bradycardia and a respiratory depression[1].

102-02-3

C8H11N5

177.211

N-Phenylbiguanide;PBG;1-Phenylbiguanide;1-苯基双胍;Phenylbiguanide

DMSO:150 mg/mL (846.45 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years