CDK4/6-IN-8 (Compound 7p) 是一种选择性的CDK4和CDK6抑制剂，其IC50值分别为 5.01 nM 和 3.97 nM。

CDK4/6-IN-8 (Compound 7p) is a selective CDK4 and CDK6 inhibitor with IC 50 values of 5.01 nM and 3.97 nM, respectively [1].

CDK4/6-IN-8 (Compound 7p) (0-656.1 μM, 48 h) shows anti-breast cancer activity [1]. Cell Viability Assay [1] Cell Line: MCF-7 Concentration: 0.1, 0.3, 0.9, 2.7, 8.1, 24.3, 72.9, 218.7 and 656.1 μM Incubation Time: 48 h Result: Inhibited cell viability with an IC 50 of 2.8 μM.

2649120-22-7

C18H18N6O5

398.37

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years