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INT-767
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
INT-767图片
CAS NO:1000403-03-1
包装:10 mg
市场价:13814元

产品介绍

产品描述

INT-767 is a dual farnesoid X receptor (FXR)/TGR5 agonist with mean EC50s of 30 and 630 nM, respectively.

体外活性

INT-767 does not show cytotoxic effects in HepG2 cells, does not inhibit cytochrome P450 enzymes, does not inhibit the human ether-a-go-go-related gene potassium channel.is highly stable to phase I and II enzymatic modifications.

体内活性

INT-767 decreases triglyceride levels and plasma total cholesterol in db/m and db/db mice.

Cas No.

1000403-03-1

分子式

C25H44NaO6S

分子量

495.67

别名

INT-767

储存和溶解度

DMSO:205.5 mg/mL (415.44 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years