您好,欢迎来到化工原料网! [登录] [免费注册]
化工原料网
位置:首页 > 产品库 > Bithionol sulfoxide
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
Bithionol sulfoxide
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Bithionol sulfoxide图片
CAS NO:844-26-8
包装:500 mg
市场价:2217元

产品介绍

产品描述

Bithionol sulfoxide is a clinically approved antiparasitic drug with the inhibitory against solid tumor growth in several preclinical cancer models.

体外活性

Bithionol caused dose-dependent cytotoxicity against all ovarian cancer cell lines tested (IC50s: 19 μM - 60 μM). BT treatment resulted in cell cycle arrest at the G1/M phase and increased ROS generation [1]. Both bithionol and bithionol sulphoxide demonstrated in vitro toxicity to Neoparamoeba spp. at all concentrations examined (0.1 to 10 mg/l over 72 h), with comparable toxicity to freshwater observed for both chemicals at concentrations >5 mg/l following a 72 h treatment [2].

Cas No.

844-26-8

分子式

C12H6Cl4O3S

分子量

372.05

别名

Bithionol sulfoxide

储存和溶解度

DMSO:250 mg/mL (671.95 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years