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20-hydroxy Leukotriene B4
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
20-hydroxy Leukotriene B4图片
CAS NO:79516-82-8
包装:1 mg
市场价:-1元

产品介绍

产品描述

20-hydroxy LTB4 is a metabolite of LTB4 in human neutrophils. In human leukocytes, LTB4 is inactivated by the enzyme LTB4 20-hydroxylase. 20-hydroxy LTB4 is not only much less active (~5%) compared to LTB4 in causing degranulation of PMNL, but actually inhibits LTB4-induced degranulation of human neutrophils (Ki = 13.3 nM). However, 20-hydroxy LTB4 is as active as LTB4 in contracting parenchymal strips from guinea pig lung. 20-hydroxy LTB4 retains considerable ligand binding affinity at the BLT2 receptor, but does not appear to function as an agonist.

Cas No.

79516-82-8

分子式

C20H32O5

分子量

352.47

别名

20-hydroxy Leukotriene B4;20-hydroxy Leukotriene B4

储存和溶解度

Ethanol:>50 mg/mL (per Rao Maddipati)
DMF:>50 mg/mL (per Rao Maddipati)
PBS (pH 7.2):>1 mg/mL (from 13(S)-HODE)
DMSO:>50 mg/mL (per Rao Maddipati)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years