Cefixime 是一种头孢菌素类抗生素, 可研究一些细菌感染。

Cefixime is a broad-spectrum, third-generation cephalosporin antibiotic derived semisynthetically from the marine fungus Cephalosporium acremonium with antibacterial activity. As does penicillin, the beta-lactam antibiotic cefixime inhibits bacterial cell wall synthesis by disrupting peptidoglycan synthesis, resulting in a reduction in bacterial cell wall stability and bacterial cell lysis. Stable in the presence of a variety of beta-lactamases, this agent is more active against gram-negative bacteria and less active against gram-positive bacteria compared to second-generation cephalosporins.

The morphological changes of serovar Typhimurium FP39 in THP-1 cells are studied by light microscopy and transmission electron microscopy. Infected THP-1 cells are treated for 4 h with 0.5 μg of cefixime/ml. (Only for Reference)

79350-37-1

C16H15N5O7S2

453.44

CL-284635;头孢克肟;Cefspan;Cephoral;Cefiximum;FK-027;FR-17027;Cefixime

Ethanol:hardly dissolve
H2O:Insoluble
DMSO:82 mg/mL(180.8 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years