Potent and selective human formyl peptide receptor FPR2 agonist (EC50 values are 1, 2 and >10 000 nM at mFRP2, hFPR2 and hFPR1 respectively). Induces migration of human monocytes and neutrophils via a chemotactic mechanism and enhances production of proinflammatory cytokines IL-1β and IL-6. Also activates the neutrophil superoxide-generating NADPH-oxidase.

271246-66-3

C75H123N19O18S

1610.97

MMK 1

25% ethanol / water:0.50 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years