Boc-C14-COOH 可以作为 ADC linker或PROTAC linker,用于合成抗体偶联药物或合成 PROTAC。
产品描述
Boc-C14-COOH is a alkyl-chain-based PROTAC linker. Boc-C14-COOH is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
体外活性
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein[1]. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[2].
Cas No.
843666-27-3
分子式
C20H37O4
分子量
341.513
别名
十六烷基二酸单叔丁酯;Boc-C14-COOH
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years