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20-(tert-Butoxy)-20-oxoicosanoic acid
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
20-(tert-Butoxy)-20-oxoicosanoic acid图片
CAS NO:683239-16-9
包装与价格:
包装价格(元)
50 mg电议
200 mg电议

产品介绍
20-(tert-Butoxy)-20-oxoicosanoic acid 可以作为ADC linker或PROTAC linker,用于合成抗体偶联药物或合成 PROTAC。

产品描述

20-(tert-Butoxy)-20-oxoicosanoic acid is a alkyl-chain-based PROTAC linker. 20-(tert-Butoxy)-20-oxoicosanoic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

体外活性

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein[1]. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[2].

Cas No.

683239-16-9

分子式

C24H46O4

分子量

398.628

别名

20-(tert-Butoxy)-20-oxoicosanoic acid

储存和溶解度

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years