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MSI-1436 lactate
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
MSI-1436 lactate图片
CAS NO:1309370-86-2
包装与价格:
包装价格(元)
5 mg电议
10 mg电议

产品名称
Trodusquemine lactate
Aminosterol-1436 lactate
产品介绍

产品描述

MSI-1436 lactate is a selective, non-competitive the enzyme protein-tyrosine phosphatase 1B (PTB1B)inhibitor(IC50 of appr 1 μM)

体外活性

Trodusquemine significantly enhanced insulin-stimulated tyrosine phosphorylation of insulin receptor (IR) beta and STAT3, direct targets of PTP1B, in HepG2 cells in vitro and/or hypothalamic tissue[1].

体内活性

Trodusquemine (MSI-1436) causes rapid and reversible weight loss in genetic models of obesity.?Trodusquemine suppressed appetite, reduced body weight (BW) in a fat-specific manner, and improved plasma insulin and leptin levels in mice[1].

Cas No.

1309370-86-2

分子式

C37H72N4O5S.7/2C3H6O3

分子量

1000.17

别名

Trodusquemine lactate;Aminosterol-1436 lactate;MSI-1436 lactate

储存和溶解度

DMSO:54 mg/mL (53.99 mM),Need ultrasonic and warming
H2O:33.33 mg/mL (33.32 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years