Spleen tyrosine kinase (Syk) inhibitor (pIC50 = 7.5). Also inhibits phosphorylated Erk (pIC50 = 7.1). Decreases cell number and viability in chronic lymphocytic leukemia (CCL) cell lines.

GSK 143

DMSO:Soluble
Powder: -20°C for 3 years
In solvent: -80°C for 2 years