RET-IN-5 是一种有效的RET抑制剂,IC50为 4.57 nM (WO2021213476A1, compound 18)。
产品描述
RET-IN-5 is a potent RET (rearranged during transfection) inhibitor with an IC 50 s of 0.4 nM and 135.1 nM for RET and VEGFR2, respectively (WO2021213476A1, compound 18) [1].
Cas No.
2725770-20-5
分子式
C29H26FN9O
分子量
535.57
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years