Citronellal 是多种芳香植物精油的单萜烯，具有促进睡眠、安定和抗伤害的作用。它可以降低机械伤害感受，且部分通过 NO-cGMP-ATP 敏感型 K?渠道通道介导的。

Citronellal is a monoterpene predominantly formed by the secondary metabolism of plants, producing antithrombotic, antiplatelet, and antihypertensive activities.

Administrations of Citronellal(CT) (50, 100, and 150?mg/kg) as well as lovastatin dramatically reduced the size of carotid atherosclerotic plaque in rats in a dose-dependent manner, compared with atherosclerotic rats fed with a high-fat diet plus balloon injury and vitamin D3. Mechanically, CT improved endothelial dysfunction, increased cell migration, and suppressed oxidative stress and inflammation in vascular endothelium in rats feeding on the high-fat diet plus balloon injury. Further, CT downregulated the protein levels of sodium-hydrogen exchanger 1 in rats with atherosclerosis[1].

An AS model in carotid artery was induced by balloon injury and vitamin D3 injection in rats fed with a high-fat diet. The size of the carotid atherosclerotic plaque was determined by ultrasound, oil red, and hematoxylin-eosin staining. Endothelial function was assessed by measuring acetylcholine-induced vessel relaxation in an organ chamber[1].

106-23-0

C10H18O

154.25

(±)-Citronellal;香茅醛;Citronellal

DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years