ALPK1-IN-1 (Compound A001) 是一种有效的 α-激酶 1 (ALPK1) 抑制剂。ALPK1 是一种胞质内丝/苏氨酸蛋白激酶，通过与叉头相关结构域 (TIFA) 依赖的促炎 NF-Κb 信号通路的 TRaf蛋白相互作用，在激活对细菌的先天免疫反应中起重要作用。

ALPK1-IN-1 (Compound A001) is a potent inhibitor of alpha-kinase 1 ( ALPK1 ). ALPK1 is an intracytoplasmic serine threonine protein kinase that plays an important role in activating the innate immune response to bacteria via TRAF-interacting protein with forkhead-associated domain (TIFA) dependent proinflammatory NF-κB signaling [1].

2765457-72-3

C25H32N6O2S

480.63

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years