m-PEG3-SH 是一种属于 PEG 类的 PROTAC linker,可用于 PROTAC 分子的合成。
产品描述
m-PEG3-SH is a PEG-based PROTAC linker. m-PEG3-SH can be used in the synthesis of PROTACs.
体外活性
PROTACs contain two different ligands connected by a linker; one of them is a ligand for an E3 ubiquitin ligase and the other one is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
Cas No.
31521-83-2
分子式
C7H16O3S
分子量
180.27
别名
M-PEG3-Thiol;2-(2-(2-Methoxyethoxy)Ethoxy)Ethanethiol;m-PEG3-SH
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years