UNC6934 是一种针对 NSD2 的 N 端 PWWP (PWWP1) 结构域的化学探针，可定位核仁。

UNC6934 is a chemical probe targeting the N-terminal PWWP (PWWP1) domain of NSD2.

UNC6934 occupies the canonical H3K36me2-binding pocket of PWWP1, antagonizes PWWP1 interaction with nucleosomal H3K36me2 and selectively engages endogenous NSD2 in cells[1].

2561494-77-5

C24H21N5O4

443.45

UNC6934

DMSO:20 mg/ml(45.10 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years