NF-Κb inhibitor is a synthetic peptide corresponding to the nuclear localization sequence (NLS) of NF-Κb p105 subunit (also known as p50) appended to a hydrophobic sequence to facilitate import into living cells. It blocks the nuclear import of p105 in cells treated with activators of NF-Κb signaling, including LPS and TNF-α. NF-Κb control is a peptide that is identical in sequence to NF-Κb inhibitor, except two essential, basic residues of the p105 NLS are substituted with non-basic amino acids. It is ineffective at blocking the activation of NF-Κb signaling and is used as a negative control peptide.

NF-κB inhibitor is a synthetic peptide corresponding to the nuclear localization sequence (NLS) of NF-κB p105 subunit (also known as p50) appended to a hydrophobic sequence to facilitate import into living cells. It blocks the nuclear import of p105 in cells treated with activators of NF-κB signaling, including LPS and TNF-α. NF-κB control is a peptide that is identical in sequence to NF-κB inhibitor, except two essential, basic residues of the p105 NLS are substituted with non-basic amino acids. It is ineffective at blocking the activation of NF-κB signaling and is used as a negative control peptide.

201608-17-5

C123H215N33O30S

2668.29

NF-κB Control

DMSO:10 mg/mL
Ethanol:1 mg/mL
PBS (pH 7.2):1 mg/mL
DMF:25 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years