Influenza Virus-IN-3 (compound 9) 是一种有效的选择性流感病毒抑制剂，H5N1、H5N2、H5N6、H5N8 的IC50s 分别为 0.88、0.10、5.5、0.51 μM。Influenza Virus-IN-3 显示出抗病毒和 NA (神经氨酸酶) 抑制活性。Influenza Virus-IN-3 具有低细胞毒性，CC50>200 μM。

Influenza virus-IN-3 (compound 9) is a potent and selective influenza virus inhibitor with IC 50 s of 0.88, 0.10, 5.5, 0.51 μM for H5N1, H5N2, H5N6, H5N8, respectively. Influenza virus-IN-3 shows antiviral and NA (neuraminidase enzyme)-inhibitory activity. Influenza virus-IN-3 shows low cytotoxicity with an CC 50 of >200 μM [1].

Influenza virus-IN-3 (compound 9a) shows NA (neuraminidase enzyme)-inhibitory activity with IC 50 s of 118.17, 1442.6, 34543.33, 78.06, 10206, 0.00048, 0.01222 nM for H5N1, H5N2, H5N6, H5N8, H5N1eH274Y, N1 (H1N1pdm09) and N2 (H3N2), respectively [1].

2412451-16-0

C25H32N2O4S

456.6

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years