您好,欢迎来到化工原料网! [登录] [免费注册]
化工原料网
位置:首页 > 产品库 > Influenza virus-IN-4
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
Influenza virus-IN-4
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAS NO:2133818-85-4
包装与价格:
包装价格(元)
5 mg电议
50 mg电议
100 mg电议

产品介绍
Influenza Virus-IN-4 (compound 11e) 是一种有效的流感病毒神经氨酸酶抑制剂,H5N1、H5N2、H5N6、H5N8 的IC50分别为 3.4, 0.094, 0.79, 0.077 μM。Influenza Virus-IN-4 显示出 NA(神经氨酸酶)抑制活性。Influenza Virus-IN-4 具有低细胞毒性,CC50为 >200 μM。Influenza Virus-IN-4 在1500 mg/kg剂量时对小鼠无明显毒性。

产品描述

Influenza virus-IN-4 (compound 11e) is a potent influenza virus neuraminidase inhibitor with IC 50 s of 3.4, 0.094, 0.79, 0.077 μM for H5N1, H5N2, H5N6, H5N8, respectively. Influenza virus-IN-4 shows NA (neuraminidase enzyme)-inhibitory activity. Influenza virus-IN-4 shows low cytotoxicity with an CC 50 of >200 μM. Influenza virus-IN-4 shows no obvious toxicity at the dose of 1500 mg/kg in mice [1].

体外活性

Influenza virus-IN-4 (compound 11e) shows NA (neuraminidase enzyme)-inhibitory activity with IC 50 s of 33.26, 16.81, 45.46, 33.02, 5270.33, 0.00043, 0.00347 nM for H5N1, H5N2, H5N6, H5N8, H5N1eH274Y, N1 (H1N1pdm09) and N2 (H3N2), respectively [1].

Cas No.

2133818-85-4

分子式

C23H31FN2O4

分子量

418.5

储存和溶解度

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years