化合物26f不仅优化了有效抑制酶（IC50= 28.2 nM），也表现出相对较少的细胞毒性（IC50= 3.32 μM），并以剂量依赖性方式诱导MDA-MB-231细胞凋亡，有效阻断G0/G1期MDA-MB-231细胞。

Compound 26F not only optimized the effective inhibitory enzyme ( ic 50 = 28.2 nm), but also showed relatively less cytotoxicity ( ic 50 = 3.32 μ M) And induced MDA-MB-231 cell apoptosis in a dose-dependent manner, effectively blocking MDA-MB-231 cells in g0/g1 phase.

C25H24FN5O2S

477.55

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years