产品描述
Bilirubin conjugate is a stable, water-soluble ditaurate derivative of bilirubin meant to mimic endogenous bilirubin glucuronide derivatives.
体内活性
In vivo, bilirubin circulates in the plasma and is taken up by hepatocytes and conjugated to one or two glucuronic acids in a reaction catalyzed by UDP glucuronidase to form bilirubin mono or diglucuronide. This water-soluble form is then excreted from the liver in bile in the feces or is converted to urobilinogen and excreted in the urine. In addition to aiding in the disposal of heme, bilirubin and its conjugated derivatives have been shown to exhibit anti-oxidant and antimutagenic effects and to play a role in gut barrier function.
Cas No.
68683-34-1
分子式
C37H46N6Na2O10S2
分子量
844.91
别名
Bilirubin Conjugate (sodium salt)
储存和溶解度
DMF:0.25 mg/mL
DMSO:10 mg/mL
H2O:5 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years