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Ipatasertib-NH2 dihydrochloride
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Ipatasertib-NH2 dihydrochloride图片
CAS NO:1001264-73-8
包装与价格:
包装价格(元)
5 mg电议
100 mg电议
500 mg电议

产品名称
GDC-0068-NH2 dihydrochloride
RG7440-NH2 dihydrochloride
产品介绍

产品描述

Ipatasertib-NH2 dihydrochloride is a ligand for target protein AKT for PROTAC (INY-03-041). INY-03-041 is composed of Ipatasertib-NH2, a ten-hydrocarbon linker, and a CRBN ligand Lenalidomide for E3 ubiquitin ligase.

体外活性

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Cas No.

1001264-73-8

分子式

C21H28Cl3N5O2

分子量

488.84

别名

GDC-0068-NH2 dihydrochloride;Ipatasertib-NH2 dihydrochloride;RG7440-NH2 dihydrochloride;Ipatasertib-NH2 dihydrochloride

储存和溶解度

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years