A-943931 is Potent and selective H4 antagonist. Potent and selective histamine H4 receptor antagonist (pKis are 7.15 and 8.12 at human and rat receptors respectively). Blocks inflammation in a peritonitis mouse model and exhibits efficacy in inflammatory pain and neuropathic pain models. Shows anti-inflammatory and analgesic effects in vivo. orally bioavailable.
纯度:≥98%
CAS:1227675-50-4