产品描述
BMS 599626 dihydrochloride is a potent and selective EGFR and ErbB2 inhibitor (IC50 values are 22 nM and 32 nM respectively). Also inhibits HER4 (IC50 = 190 nM). Inhibits EGFR and ErbB2 with 100-fold greater potency than MEK and Lck. Antiproliferative agentin vitroand anti-tumorigenic agentin vivo. Orally bioavailable.
Cas No.
1781932-33-9
分子式
C27H29Cl2FN8O3
分子量
603.47
别名
BMS 599626 dihydrochloride
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years