Dexamethasone oxetanone (Dex-Ox) 是糖皮质激素选择性类固醇地塞米松 (Dex) 的衍生物,是一种抗糖皮质激素。Dexamethasone oxetanone 是一种抗孕激素,具有显着的孕酮受体 (PR) A 和 B 异构体激动剂活性。
产品描述
Dexamethasone oxetanone (Dex-Ox), a derivative of the glucocorticoid-selective steroid Dexamethasone (Dex), is an antiglucocorticoid. Dexamethasone oxetanone is an antiprogestin with significant agonist activity with progesterone receptor (PR) A and B isoforms [1] [2].
体外活性
Dexamethasone oxetanone (1 μM) exhibits significant quantities of agonist activity with transfected PR in CV-1 cells [2].
Cas No.
4089-36-5
分子式
C22H27FO4
分子量
374.45
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years