Lapaquistat acetate is a squalene synthase inhibitor. It also blocks the conversion of farnesyl diphosphate (FPP) to squalene. Lapaquistat acetate is used to Mevalonate Kinase Deficiency (MKD), it is effective at lowering low-density lipoprotein cholesterol, but it might cause liver damage.

189060-13-7

C33H41ClN2O9

645.14

TAK-475;Lapaquistat acetate

DMSO:46 mg/mL (71.30 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years