Ac-LEHD-AMC is a fluorogenic substrate for caspase-9.[1] Upon cleavage by caspase-9, 7-amino-4-methylcoumarin (AMC) is released and its fluorescence can be used to quantify caspase-9 activity. AMC displays excitation/emission maxima of 340-360/440-460 nm, respectively.

292633-16-0

C33H41N7O11

711.729

Ac-LEHD-AMC (trifluoroacetate salt)

H2O:1 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years