TNIK-IN-4 是一种有效的TNIK抑制剂，IC50为 0.61 μM。TNIK-IN-4 对典型的结直肠癌细胞系 HCT116 具有抑制活性。

TNIK-IN-4 is a potent TNIK inhibitor with IC 50 of 0.61 μM. TNIK-IN-4 has inhibitory activity against typical colorectal cancer cell line HCT116 [1].

TNIK-IN-4 (compound 5a) (0.4-100 μM; 72 hours) has inhibitory activity against typical colorectal cancer cell line HCT116 with IC 50 of 36.423 μM [1]. Cell Proliferation Assay Cell Line: HCT116 cells [1] Concentration: 0.4, 1.2, 3.7, 11.1, 33.3 and 100 μM Incubation Time: 72 hours Result: Showed inhibitory activity against typical colorectal cancer cell line HCT116 with IC 50 of 36.423 μM.

2754266-04-9

C20H16FN3O3

365.36

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years