您好,欢迎来到化工原料网! [登录] [免费注册]
化工原料网
位置:首页 > 产品库 > Artelinic acid
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
Artelinic acid
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Artelinic acid图片
CAS NO:120020-26-0
包装与价格:
包装价格(元)
25 mg电议
50 mg电议
100 mg电议

产品介绍

产品描述

Artelinic acid, a derivative of Artemisinin, is an antimalarial drug for the treatment of multidrug-resistant strains of Plasmodium falciparum.

体内活性

Artelinic acid (10 mg/kg; i.v.) has an elimination time t1/2 of 0.37 hours, a CL of 14.99 mL/min/kg, a Vss of 9.52 L, and an AUC0-12h of 11219 ng h/mL for dogs. Artelinic acid (10 mg/kg; intramuscular) has an elimination time t1/2 of 6.14 hours, a CL of 14.58 mL/min/kg, a Vss of 36.1 L and an AUC0-12h of 96372 ng h/mL for dogs. Artelinic acid (10 mg/kg; oral) has an elimination time t1/2 of 2.21 hours, a CL of 14.6 mL/min/kg, a Vss of 16.2 L and a AUC0-12h of 8839 ng h/mL for dogs [1].

Cas No.

120020-26-0

分子式

C23H30O7

分子量

418.48

别名

Artelinic acid

储存和溶解度

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years