Anti-inflammatory agent 11 (化合物 16) 是一种有效的抗结核分枝杆菌和抗炎剂。Anti-inflammatory agent 11 抑制Mtb H37Rv和M299生长，其MIC50(最低抑制浓度 50%) 分别为 1.3 和 6.9 μM。Anti-inflammatory agent 11 通过抑制 iNOS 表达抑制NO，同时抑制 TNF-α 和 IL-1β 的产生。Anti-inflammatory agent 11 可用于结核病的研究。

Anti-inflammatory agent 11 (compound 16) is a potent antimycobacterial and anti-inflammatory agent. Anti-inflammatory agent 11 inhibits Mtb H37Rv and M299 growth, with MIC 50 (minimum inhibitory concentration 50%) of 1.3 and 6.9 μM, respectively. Anti-inflammatory agent 11 inhibits NO through the suppression of iNOS expression, and also inhibited the production of TNF-α and IL-1β. Anti-inflammatory agent 11 can be used for tuberculosis (TB) research [1].

Anti-inflammatory agent 11 (compound 16) is active in the reduction of accumulated nitrite, with an IC 50 of 64.8 ± 1.0 μM [1].

63932-07-0

C14H14N4OS

286.35

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years