hCAI/II-IN-5 (compound MZ8) 是一种有效的hCA I和hCA II(人碳酸酐酶同工酶 I 和 II) 抑制剂，其IC50值分别为 37.88 和 45.23 nM。 hCAI/II-IN-5 对α-glycosidase和AChE也表现出抑制作用，IC50分别为 48.98 和 420.14 nM。hCAI/II-IN-5 可用于糖尿病、阿尔茨海默病、心力衰竭、溃疡、癫痫等多种疾病的研究。

hCAI/II-IN-5 (compound MZ8) is a potent hCA I and hCA II (human carbonic anhydrase isoenzymes I and II) inhibitor, with IC 50 values of 37.88 and 45.23 nM, respectively. hCAI/II-IN-5 also shows inhibition profile against α-Glycosidase and AChE, with IC 50 values of 48.98 and 420.14 nM, respectively. hCAI/II-IN-5 can be used for the research of many diseases such as diabetes, Alzheimer’s disease, heart failure, ulcer, and epilepsy [1].

2428389-67-5

C21H18Cl2N8O4S2

581.45

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years