(E)-Guanabenz ((E)-Wy-8678) 是一种具有口服活性的中枢α2-肾上腺素受体 (α2-adrenoceptor)激动剂。(E)-Guanabenz 具有抗高血压活性，通过刺激中枢 α2- 肾上腺素受体，并减少交感神经向外周的净流出而起作用。(E)-Guanabenz z也直接结合并抑制 GADD34，具有神经保护活性。(E)-Guanabenz 可用于研究高血压和帕金森病。

(E)-Guanabenz ((E)-Wy-8678) is an orally active central α2-adrenoceptor agonist. (E)-Guanabenz has antihypertensive activity, acts by stimulating central α2-adrenoceptors, and reducing net sympathetic outflow into the periphery. (E)-Guanabenz also directly binds to and inhibits GADD34, and has neuroprotective activity. (E)-Guanabenz can be used to study hypertension and Parkinson disease [1] [2].

60329-03-5

C8H8Cl2N4

231.08

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years