PD 109488 is a metabolite of quinapril and is a derivative of Quinapril that acts as an ACE inhibitor. Inhibition of ACE prevents the conversion of signaling peptide angiotensin I into angiotensin II, which acts as a potent vasoconstrictor. Reduced levels of angiotensin II also reduces the amount of aldosterone that is expressed due to RAAS signaling.

103733-49-9

C25H28N2O4

420.5

Quinapril Diketopiperazine;PD-109488;PD109488;PD 109488

DMSO:Soluble
Powder: -20°C for 3 years
In solvent: -80°C for 2 years