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QS-21
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
QS-21图片
CAS NO:141256-04-4
包装:10 mg
市场价:7000元

产品名称
Stimulon
产品介绍

产品描述

QS-21, an immunostimulatory saponin, could be used as a potent vaccine adjuvant. QS-21 stimulates Th2 humoral and Th1 cell-mediated immune responses through action on antigen presenting cells (APCs) and T cells. QS-21 can activate the NLRP3 inflammasome with subsequent release of caspase-1 dependent cytokines, IL-1β and IL-18.

体内活性

Studies in mouse APCs (DCs and macrophages) identifie QS-21 as an activator of the NLRP3 inflammasome, and cause subsequent release of caspase-1 dependent proinflammatory cytokines I1-1β/I1-18 that can promote Th 17 cell maturation or drive INF-γ-mediated Th1 responses, respectively[3].

Cas No.

141256-04-4

分子式

C92H148O46

分子量

1990.13

别名

Stimulon;QS-21;QS-21

储存和溶解度

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years