产品描述
β-Bisabolene is a sesquiterpene isolated from opoponax ( Commiphora guidotti ). β-Bisabolene, an anti-cancer agent , can be used for the study of breast cancer.
体外活性
β‐isabolene exhibits selective cytotoxic activity for mouse cells, it against normal Eph4, MG1361 and 4T1 cells with IC 50 values of >200?μg/ml, 65.49?μg/ml, and 48.99?μg/ml, respectively. It against normal MCF‐10A, MCF‐7, MDA‐MB‐231, SKBR3 and BT474 cells with IC 50 values of 114.3?μg/ml, 66.91?μg/ml, 98.39?μg/ml, 70.62?μg/ml and 74.3?μg/ml, respectively[1].
体内活性
β‐isabolene is effective in reducing the growth of transplanted 4T1 mammary tumours?in vivo?(37.5% reduction in volume by endpoint)[1].
Cas No.
495-61-4
分子式
C15H24
分子量
204.35
别名
β-Bisabolene
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years