B-Raf IN 7 (compound 6a) 是一种有效的B-Raf抑制剂，其IC50为 110.23 nM。B-Raf IN 7 对结肠癌 (HCT-116)、乳腺癌 (MCF-7)、肝细胞癌 (HEPG-2)、人宫颈癌 (Hela) 和人前列腺癌 (PC-3) 细胞表现出较强的抗肿瘤活性，IC50值分别为 7.50、9.87、10.57、11.63 和 12.83 μM。

B-Raf IN 7 (compound 6a) is a potent B-Raf inhibitor, with an IC 50 of 110.23 nM. B-Raf IN 7 exhibits antitumor activity against colon carcinoma (HCT-116), mammary gland (MCF-7), hepatocellular carcinoma (HEPG-2), human cervical carcinoma (Hela) and human prostate cancer (PC-3) cells, with IC 50 values of 7.50, 9.87, 10.57, 11.63 and 12.83 μM [1].

2477725-07-6

C15H16N6O3

328.33

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years