Amisulpride 是多巴胺D2/D3受体拮抗剂,对于人多巴胺D2和D3的Ki分别为 2.8 和 3.2 nM。
产品描述
Amisulpride (trade name Solian) is an antipsychotic drug sold by Sanofi-Aventis. It is not approved for use in the United States, but is approved for use in Europe and Australia for the treatment of psychoses and schizophrenia. Additionally, it is approved in Italy for the treatment of dysthymia (under the brand name Deniban). Amisulpride is a selective dopamine antagonist.
Cas No.
71675-85-9
分子式
C17H27N3O4S
分子量
369.48
别名
阿米舒必利;DAN 2163;氨磺必利;Amisulpride
储存和溶解度
Ethanol:65 mg/mL(175.9 mM)
DMSO:74 mg/mL (200.28 mM)
H2O:<1 mgml
Powder: -20°C for 3 years
In solvent: -80°C for 2 years