产品描述
CCR6 inhibitor 1 is a potent and selective CCR6 inhibitor (IC50s: 0.45 and 6 nM for monkey and human CCR6), much more selective at CCR6 over human CCR1 (IC50, >30000 nM), and CCR7 (IC50, 9400 nM).
体外活性
CCR6 inhibitor 1 (Compound 35) inhibits the human B cell migration L20-induced.
Cas No.
2437547-04-9
分子式
C24H23F3N4O3S
分子量
504.52
别名
CCR6 inhibitor 1
储存和溶解度
DMSO:125 mg/mL (247.76 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years