NH2-PEG6-Boc 是一种基于 PEG 的 PROTAC 接头，可用于 PROTAC 的合成。 它也是一种不可切割的 6 单元 PEG ADC 接头，用于合成抗体-药物偶联物。

NH2-PEG6-Boc is a PEG-based PROTAC linker that can be used in PROTAC synthesis[1]. NH2-PEG6-Boc is also a non-cleavable 6-unit PEG ADC linker used in antibody-drug conjugates(ADCs) synthesis[2].

PROTACs contain two different ligands connected by a linker; one of them is a ligand for an E3 ubiquitin ligase and the other one is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[2].

1286281-32-0

C19H39NO8

409.51

氨基-五聚乙二醇-丙酸叔丁酯;NH2-PEG6-Boc

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years